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Opioids are a class of drugs naturally found in the opium poppy plant. They work in the brain to produce a variety of effects, including the pain relief.

They can be prescription medications often referred to as painkillers, or they can be so-called street drugs, such as heroin.

Many prescription opioids are used to block pain signals between the brain and the body and are typically prescribed to treat moderate to severe pain. In addition to controlling pain, they will make you feel relaxed, happy or “high,” and can be addictive. Additional side effects can include slowed breathing, constipation, nausea, confusion and drowsiness.

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Xanax (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

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Tramadol is used to treat moderate to severe pain in adults. It comes as a tablet, and as an extended-release tablet or capsule to treat around-the-clock pain.

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Dilaudid (hydromorphone) is an opioid pain medication. An opioid is sometimes called a narcotic. Dilaudid is used to treat moderate to severe pain. Dilaudid may also be used for purposes not listed in this medication guide.